What Would You Do?
Now with 15% more polyunsaturated updates
We have a big decision to make and as there is no definitive right answer, I figured "What the hell, I'll ask the Internet!"
First, the facts:
I am thirty years old. I have Endometriosis and PCOS, but no structural uterine problems such as scarring or shape abnormalities. We have no male factor issues. I am willing to cycle again, but clearly I have a history of OHSS, so it might not go too well. We have six 'good' frozen embryos and our clinic has an 80 to 90% survival rate upon thaw.
Update:
Our embryos are Day Three.
We have one 4 cell, a 5 cell, and four 8 cell.
They range in quality from grade 1 (no fragmentation) to grade 3 (25 to 50% fragmentation). Most of them are grade 2 (0 to 25% fragmentation).
They are frozen in pairs.
Now, during the fresh cycle, Dr. BrightEyes always discussed transferring no more than a single embryo because the risk of multiples would be too high, and neither of us are particularly interested in having twins.
We're not anti-twin or anything, we're just uncomfortable with electively starting a pregnancy that would be guaranteed to be high risk. I haven't been hiding under a rock on Mars with my fingers in my ears or anything, so I know that a singleton pregnancy can carry a significant amount of risk as well, but given my current ability to rack up the reproductive disasters, a twin pregnancy seems like...well, just inviting asking for getting down on our hands and knees and motherfucking begging for trouble.
I'm fine with taking risks with my own health but am less inclined to do the same with my potential children. If I spontaneously conceived twins, well, that would be...ha! Yeah, me, spontaneously conceiving anything? What the fuck was I thinking? Anyway, we would be unlikely to ever transfer more than two, because we've already decided that we would selectively reduce high order multiples, and Dr. BrightEyes informed me that transferring more than two doesn't raise the pregnancy rate, but does increase the multiple rate.
Our clinic's fresh transfer success rate for my age group is about 60%. Frozen transfer success rates are considerably lower, at 15 to 20% for single embryo transfer, 30 to 40% with two embryos.
When performing frozen transfers, our clinic typically transfers two because it raises the pregnancy rate. Naturally, it also raises the multiple rate, but it's not a one to one correlation. Transferring two carries a 30% chance of twins in the (somewhat unlikely) event of pregnancy. Conveniently, there are no absolutes here.
Transferring two doesn't guarantee us twins, but it does get us a better overall chance of pregnancy.
While crunching the numbers, Dr. BrightEyes said "Sometimes it comes down to which bothers you more, the idea of having twins, or the idea of not being pregnant at all?"
I don't know.
Soper asked me what my gut said, and I said "My gut says 'Get these huge ovaries off my head!' It's way too crowded in here." "That's not helpful," Soper said. She's right.
There is also one more factor at play here, and that is the nigh unbreakable Law Of Akeeyu's Fucked Up Snatch which states (among other things) that the chances of crotch related things going wrong, whatever they may be, should probably be multiplied by thirtytwelve, and that whenever there is a slim statistical chance of a medical disaster transpiring, I will end up on the wrong side of the odds.
So, what do you think?
If you have any particular experience with any of these issues, please leave your pertinent in/fertility vitals: Did you use ART? Did you have a FET? What were the results? If you had twins or HOM, how did it go? If you had twins, did they suffer any long term complications? How long were they in the NICU? How long were you on bedrest? How close did you get to your due date? Can you think of anything else we should know before we make this decision?
Please note: This is not the time or place for a nasty debate on selective reduction or the ethical issues of ART, so don't go there. I will delete and ban people who can't play nice.
Thank you.